Drug intelligence / Profile preview

5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine

Development stage
Preclinical
Lead developer
Shenyang Pharmaceutical University
Modality
Small Molecules
01

Overview

5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine is a synthetic small molecule belonging to the class of quinazoline-2,4-diamine derivatives. While specific information on this exact compound is limited, related quinazoline-2,4-diamine derivatives have been investigated as p21-activated kinase 4 (PAK4) inhibitors. These compounds have demonstrated potent inhibitory activity against PAK4 and antiproliferative effects in cancer cell lines, such as A549 lung cancer cells, suggesting potential as an anticancer agent. The mechanism of action involves the inhibition of PAK4, a kinase implicated in cell proliferation, migration, and invasion in various cancers.

02

Targets

DcpS (m7GpppX diphosphatase)

Beyond the preview

Go deeper on 5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on 5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call